MABS416

Anti-ABCG5, clone 1B5E10 Antibody

clone 1B5E10, from mouse

• 同義詞: ATP-binding cassette sub-family G member 5, Sterolin-1, ABCG5
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 1B5E10, monoclonal
• 物種活性: human
• 技術: ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable; western blot: suitable
• 同型: IgG1
• UniProt登錄號: Q9H222
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ABCG5(64240)

描述

一般說明

ATP-binding cassette sub-family G member 5, also known as Sterolin-1, and encoded by the gene name ABCG5, plays an important role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. ABCG5 is localized too the membrane and is expressed in the liver, lower levels in the small intestine and colon. Mutations associated with ABCG5 is Sitosterolemia, which is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile.

免疫原

Purified recombinant fragment of human ABCG5 expressed in E. Coli

應用

Anti-ABCG5, clone 1B5E10 Antibody is an antibody against ABCG5 for use in western blotting, IHC, flow cytometry & ELISA.

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected ABCG5 in cervical and rectum cancer tissues.

Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected ABCG5 in A549 cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

品質

Evaluated by Western Blotting in HL7702, Raji and Jurkat cell lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ABCG5 in HL7702, Raji and Jurkat cell lysates.

標靶描述

~70 kDa observed. Uncharacterized bands may be observed in some lysate(s).

聯結

Replaces: MABN1076

外觀

Format: Purified

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable