MABN79

Anti-BDNF Antibody, clone 8G8.2

clone 8G8.2, from mouse

• 同義詞: BDNF, Brain-derived neurotrophic factor, Abrineurin
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 8G8.2, monoclonal
• 物種活性: mouse
• 技術: western blot: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_001137277
• UniProt登錄號: P23560
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BDNF(627)

描述

一般說明

BDNF is a important neurotrophic factor essential for proper neuronal development and survival of various neuronal populations in the CNS and PNS. BDNF is also key for axonal growth and path finding of dendritic growth and morphology. BDNF also is key to neuronal responses and LTP or LTD and synaptic plasticity, behavior, learning and memory. BDNF is also important in neuronal disease and is being studied as potential marker in various diseases. Finally, BDNF is expressed initially as a proform protein long thought to simply be an inactive proform factor, however recent research demonstrates that proBDNF may play roles not only in neuronal development but also development in general as well as in adult metabolism in brain, muscle, and general metabolic function, so the research into BDNF is growing. BDNF is expressed developmentally in the brain and developing nervous system but it is also expressed in the adult in the brain, gut, muscle, lung, testis, prostate and placenta.

免疫原

KLH-conjugated linear peptide corresponding to human BDNF.

應用

Anti-BDNF Antibody, clone 8G8.2 is an antibody against BDNF for use in Western Blotting.

品質

Evaluated by Western Blotting in mouse brain membrane tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected BDNF in 10 µg of mouse brain membrane tissue lysate.

標靶描述

~25 kDa observed. UnitProt describes 5 isoforms produced by alternative promoter usage and alternative splicing ranging from 27.8 to 37.1 kDa

外觀

Format: Purified

其他說明

Concentration: Please refer to lot specific datasheet.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable