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Key Documents

MABN160

Sigma-Aldrich

Anti-Syntenin-1 Antibody, clone 4F4.1

clone 4F4.1, 1 mg/mL, from mouse

同義詞:

Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

4F4.1, monoclonal

物種活性

human

濃度

1 mg/mL

技術

western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SDCBP(6386)

一般說明

The syndecans are transmembrane proteoglycans that place structurally heterogeneous heparan sulfate chains at the cell surface and a highly conserved polypeptide in the cytoplasm. Syntenin (also known as SDCBP) is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.

免疫原

GST-tagged recombinant protein corresponding to human Syntenin-1. The immunogen has a 98% homology to Mouse and Rat.

應用

Detect Syntenin-1 using this Anti-Syntenin-1 Antibody, clone 4F4.1 validated for use in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Syntenin-1 in 10 µg of HEK293 cell lysate.

標靶描述

~32 kDa observed

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Diantha Van De Vlekkert et al.
Bio-protocol, 10(7), e3576-e3576 (2021-03-05)
Exosomes are dynamic nanovesicles secreted by virtually all cells and are present in all biological fluids. Given their highly heterogeneous content exosomes have been implicated in many physiological and pathological processes that they exert by influencing cell-cell and cell-ECM communication.

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