MABF31

Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8

clone 8C8, from mouse

• 同義詞: defensin, alpha 5, Paneth cell-specific, defensin, alpha 5, preproprotein, defensin-5, defensin 5, Defensin, alpha 5
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 8C8, monoclonal
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgG2bκ
• NCBI登錄號: NP_066290
• UniProt登錄號: Q01523
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... DEFA5(1670)

描述

一般說明

Human alpha defensin-5 (HD5) is one of six peptides belonging to the alpha defensin family. Defensins are small peptides involved in immunological defense against viral and microbial infections through either direct interaction with pathogens or in combination with other immune system factors. There are three subfamilies of defensins (α, β, and θ). α defensins are only observed in mammals and are mainly β-sheet structures. Alpha defensin-5 (HD5) is primarily expressed in the Paneth cells found within the small intestine, and has been shown to possess activity against both Gram-positive and Gram-negative microbes. Studies have shown alpha defensin-5 (HD5) to be a strong antagonist towards human Papillomavirus infection. It may also play a role Crohn’s disease.

免疫原

Recombinant protein corresponding to human alpha defensin-5 (HD5).

應用

Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8 detects level of Alpha Defensin-5 (HD5) & has been published & validated for use in IH & WB.

Western Blot Analysis: 0.5 ug/mL from a previous lot detected alpha defensin-5 (HD5) in human small intestine tissue lysate. The urea-treated method is recommended instead of SDS page (Shen, B. et al., 2005).

品質

Evaluated by Immunohistochemistry in normal human tranverse colon tissue.

Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected alpha defensin-5 (HD5) in normal human tranverse colon tissue.

標靶描述

10 kDa calculated

外觀

Format: Purified

分析報告

Control
Normal human tranverse colon tissue

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable