MABC282

Anti-BAG3 Antibody, clone AC-1

clone AC-1, from mouse

• 同義詞: BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 無性繁殖: AC-1, monoclonal
• application: IHC; IP
• 物種活性: human
• 技術: immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable
• citations: 1

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: AC-1, monoclonal
• 物種活性: human
• 技術: immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable
• 同型: IgG1κ
• NCBI登錄號: NP_004272
• UniProt登錄號: O95817
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BAG3(9531)

描述

一般說明

Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH.

應用

Detect BAG3 using this Anti-BAG3 Antibody, clone AC-1 validated for use in Immunoprecipitation, IHC(P).

品質

Evaluated by Immunoprecipitation in HeLa cell lysate.

Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated BAG3 from HeLa cell lysate.

標靶描述

~62 kDa observed

外觀

Format: Purified

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable