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Key Documents

MAB416

Sigma-Aldrich

Anti-Interferon-β Antibody, clone A1

clone A1, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

A1, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

ELISA: suitable
western blot: suitable

同型

IgGκ

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... IFNB1(3456)

特異性

Human interferon-beta (IFN-beta). Recognizes amino acids 30-47 of IFN-beta. No cross-reactivity with Human IFN-alpha or IFN-gamma.

免疫原

Human interferon beta.

應用

Anti-Interferon-β Antibody, clone A1 detects level of Interferon-β & has been published & validated for use in ELISA & WB.
Immunoblotting

ELISA

Neutralization of IFN-beta bioactivity; 90% reduction of bioactivity at 1.4 μg/mL for recombinant IFN-beta and 2.7 μg/mL for natural IFN-beta. Assay method used is provided in Grossberg, S.E. et al, Manual of Clinical Immunology.

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

外觀

Format: Purified
Hybridoma culture grown in low IgG FBS (3%), Protein G purified. Liquid in 50 mM Na Acetate, pH 6.5, 50 mM NaCl, 4% sucrose, 0.1% Tween20, no preservatives added

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to twelve months after date of receipt. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Neutralizing antibodies to interferon beta in multiple sclerosis: analytical evaluation for validation of a cytopathic effect assay.
Catherine Massart,Jacqueline Gibassier,Joel Oger,Emmanuelle Le Page,Gilles Edan
Clinica Chimica Acta; International Journal of Clinical Chemistry null
Analysis of antigenic domains on natural and recombinant human IFN-beta by the inhibition of biologic activities with monoclonal antibodies.
Redlich, P N and Grossberg, S E
Journal of immunology (Baltimore, Md. : 1950), 143, 1887-1893 (1989)
Reduced effectiveness of long-term interferon-beta treatment on relapses in neutralizing antibody-positive multiple sclerosis patients: a Canadian multiple sclerosis clinic-based study.
C Boz,J Oger,E Gibbs,S E Grossberg,
Multiple Sclerosis (Houndmills, Basingstoke, England) null
Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3.
Susan E Sweeney,Ling Mo,Gary S Firestein
Arthritis and Rheumatism null

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