推薦產品
生物源
mouse
品質等級
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
MRPm6, monoclonal
物種活性
human
製造商／商標名
Chemicon®
技術
flow cytometry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
同型
IgG1
UniProt登錄號
運輸包裝
wet ice
基因資訊
human ... ABCC1(4363)
特異性
MRPm6 reacts with an internal epitope of MRP, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm6 was raised against a bacterial fusion protein of MRP, containing a segment of 170 amino acids in the carboxy terminal end and part of the carboxy proximal nucleotide binding domain of the protein. MRPm6 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al., 1994).
應用
Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 is an antibody against Multi-Drug Resistance Related Protein for use in FC, WB, IH(P).
Western blot
Flow Cytometry
Immunohistochemistry on frozen and paraffin embedded tissue
sections: 1:20.
Note: For cellular detection permeabilization is required.
Optimal working dilutions must be determined by end user.
Flow Cytometry
Immunohistochemistry on frozen and paraffin embedded tissue
sections: 1:20.
Note: For cellular detection permeabilization is required.
Optimal working dilutions must be determined by end user.
外觀
Tissue Culture Supernatant. Liquid containing 0.1% sodium azide and 0.7% BSA.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
M L Den Boer et al.
Leukemia, 11(7), 1078-1085 (1997-07-01)
The clinical relevance of multidrug resistance (MDR)-related proteins in childhood acute lymphoblastic leukemia (ALL) is largely unknown. The diversity of techniques, fixation methods, storage of cells (fresh or cryopreserved) etc, may contribute to discrepancies observed between several studies. We therefore
Tissue distribution of the multidrug resistance protein.
Flens, M J, et al.
The American Journal of Pathology, 148, 1237-1247 (1996)
D Schadendorf et al.
The American journal of pathology, 147(6), 1545-1552 (1995-12-01)
Melanoma cells often display a multidrug-resistant phenotype, but the mechanisms involved are largely unknown. We have studied here the recently identified transport-associated proteins, MRP and LRP, and the well-known drug resistance marker P-glycoprotein using a panel of 16 human melanoma
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