MAB345A4

Anti-O4 Antibody, clone 81, Alexa Fluor^™488 Conjugate

clone 81 (mAB 04), from mouse, ALEXA FLUOR^™ 488

• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 488
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 81 (mAB 04), monoclonal
• 物種活性: rat
• 物種活性（以同源性預測）: human (based on 100% sequence homology), bovine (based on 100% sequence homology), chicken (based on 100% sequence homology), mouse (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable
• 同型: IgM
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified

描述

一般說明

Oligodendrocytes and astrocytes are derived from common precursor cells, glioblasts (Sommer, 1981). O-Antigens are sulfatides, which function as differentiation markers on the surface of oligodendrocytes of the central nervous system. O4 is formed postnatally (Schachner, 1981) and is a marker for cell bodies and processes of oligodendrocytes types I and II (hairy eyeball type). During oligodendrocyte differentiation, O4 occurs in pro-oligodendrocytes, but not in O-2A-progenitor cells. O4 occurs from day 3 onwards in cell cultures of embryonic mouse brain. Anti-O4 can be used in myelination, demyelination and remyelination studies and in regeneration experiments.

特異性

This antibody recognizes Oligodendrocyte marker O4. Also reacts with certain galactolipids in sperm.

免疫原

Homogenate of white matter of corpus callosum from bovine brain.

應用

Anti-O4 Antibody, clone 81, Alexa Fluor^™488 Conjugate detects level of O4 & has been published & validated for use in ICC.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

品質

Evaluated by Immunocytochemistry in undifferentiated rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected O4 in undifferentiated rat oligodendrocyte precursor cells.

外觀

Precipitation followed by ion exchange purification

Purified mouse monoclonal IgM conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

儲存和穩定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
Undifferentiated rat oligodendrocyte precursor cells

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable