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Merck
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Key Documents

MAB3301

Sigma-Aldrich

Anti-TIMP-1 Antibody, clone 147-6D11

clone 147-6D11, Chemicon®, from mouse

同義詞:

Tissue Inhibitor of Metalloproteinase-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

147-6D11, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TIMP1(7076)

特異性

The antibody specifically reacts with human TIMP-1. This is a purified mouse monoclonal antibody to recombinant human tissue inhibitor of metalloproteinases-1 (recombinant TIMP-1).

SPECIES REACTIVITY:

Does not cross-react with mouse and rat TIMP-1.

免疫原

Mouse Mac-1

應用

Immunoblotting: Suggested Dilution 1μg/mL

Immunohistochemistry on paraffin-embedded tissue sections using PLP fixation; not tested on traditional formalin fixed tissues. Antigen retrieval is HIER methods

ElA
This Anti-TIMP-1 Antibody, clone 147-6D11 is validated for use in ELISA, WB, IH(P) for the detection of TIMP-1.

聯結

Replaces: MAB1338

外觀

Format: Purified

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Marcia Riboldi et al.
Reproduction (Cambridge, England), 160(5), 673-684 (2020-10-17)
During embryo implantation, endometrial angiogenesis is regulated by signals originating from the endometrium itself and the developing embryo. It has been suggested that hCG may play a pro-angiogenic role; therefore, we sought to understand its regulatory role in blood vessel
Expression of TIMP-1 in Pichia pastoris. Selection of an anti-TIMP-1 specific single-chain Fv antibody from a large non-immune library.
Gordana Wozniak, Eva Obermayr, Matjaz Jeras, Mio Knezevic, Florian Ruker
Clinica Chimica Acta; International Journal of Clinical Chemistry null
A Tapia-Pizarro et al.
Human reproduction (Oxford, England), 28(8), 2215-2227 (2013-05-23)
Are secreted extracellular matrix (ECM) remodelling elements, relevant to embryo implantation and placentation, modified by hCG in endometrial stromal cells (ESCs)? hCG decreases tissue inhibitor of metalloproteinase 1 (TIMP-1) secretion in ESCs, thereby facilitating extravillous trophoblast invasion in vitro. Successful
Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases.
F A Attiga, P M Fernandez, A T Weeraratna, M J Manyak, S R Patierno
Cancer Research null
Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients.
Iizasa, T, et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 5, 149-153 (1999)

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