MAB3236

Anti-Cytokeratin 18 Antibody, clone RCK106

clone RCK106, Chemicon^®, from mouse

• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: RCK106, monoclonal
• 物種活性: human
• 製造商／商標名: Chemicon^®
• 技術: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• 同型: IgG1
• NCBI登錄號: NM_000224.2; NM_199187.1
• UniProt登錄號: P05783
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KRT18(3875)

描述

一般說明

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies.

特異性

Cytokeratin 18. MAB3236 reacts exclusively with human glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells as well as adenocarcinomas originating from them.

SPECIES REACTIVITY:

Human only. Does not react with other species.

免疫原

Cytoskeletal preparation of human bladder carcinoma cell line T24.

應用

Anti-Cytokeratin 18 Antibody, clone RCK106 detects level of Cytokeratin 18 & has been published & validated for use in FC, WB, IC, IH(P).

Research Category
Cell Structure

Research Sub Category
Cytokeratins

Western blot

Immunohistochemistry on frozen and paraffin embedded tissue sections.

Immunocytochemistry

Flow cytometry

Optimal working dilutions must be determined by the end user.

聯結

Replaces: 04-586

外觀

Format: Purified

Liquid in buffer with 0.1% sodium azide.

儲存和穩定性

Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable