MAB2605

Anti-ATG5 Antibody, clone 177.19

clone 177.19, from mouse

• 同義詞: APG5 autophagy 5-like, APG5 autophagy 5-like (S. cerevisiae), APG5 (autophagy 5, S. cerevisiae)-like, ATG5 autophagy related 5 homolog (S. cerevisiae), ATG5 autophagy related 5-like, Apoptosis-specific protein
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 177.19, monoclonal
• 物種活性: human
• 技術: immunoprecipitation (IP): suitable; western blot: suitable
• 同型: IgG2bκ
• NCBI登錄號: NM_004849.2
• UniProt登錄號: Q9H1Y0
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ATG5(9474)

描述

一般說明

ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity

特異性

Other species have not been tested.

The antibody reacts with the 50 kDa ATG5 protein.

免疫原

Linear Peptide, aa: 8-318

應用

Immunoprecipitation: HeLa cell lysate

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5.

品質

Western Blot Analysis: 0.5 ug/mL of this antibody detected ATG5 on HeLa cell lysate.

標靶描述

50 kDa

聯結

Replaces: MABC137

外觀

Protein G Purified

Format: Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Western Blot and Immunoprecipitation: HeLa cell lysate.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable