MAB13426

Anti-MMP-13 Antibody, clone LIPCO IID1

clone LIPCO IID1, Chemicon^®, from mouse

• 同義詞: Collagenase-3
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: LIPCO IID1, monoclonal
• 物種活性: mouse, rat
• 製造商／商標名: Chemicon^®
• 技術: western blot: suitable
• 同型: IgG1
• NCBI登錄號: NM_002427.2
• UniProt登錄號: P45452
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MMP13(4322)

描述

特異性

It recognizes proteins of ~60 kDa and ~48 kDa which are identified as pro (latent) and activate forms of matrix metalloproteinase-13 (MMP-13; also known as Collagenase-3). Antibody shows no cross-reactivity with the pro and active forms of other MMPs. Human collagenase-3 (MMP13) is a recently identified member of the matrix metalloproteinase (MMP) family that is expressed in breast carcinomas and in articular cartilage from arthritic patients. The MMP-13 gene has been isolated and characterized. This gene is composed of 10 exons and 9 introns and spans over 12.5 kb. The overall organization of the collagenase-3 gene is similar to that of other MMP genes clustered at chromosome 11q22, including fibroblast collagenase (MMP-1), matrilysin (MMP-7), and macrophage metalloelastase (MMP-12), but is more distantly related to genes coding for stromelysin-3 (MMP-11), gelatinase-A (MMP-2), and gelatinase-B (MMP-9), which map outside of this gene cluster.

Cellular Localization:

Cytoplasmic

免疫原

Rat MMP-13 from BC-1 cells.

應用

Anti-MMP-13 Antibody, clone LIPCO IID1 is an antibody against MMP-13 for use in WB.

Research Category
Cell Structure

Research Sub Category
MMPs & TIMPs

Western Blotting (Lyons, 1991; Lyons, 1993): 1:200-1:400 at room temperature for 2 hours.

Immunofluorescence

Optimal working dilutions must be determined by end user.

外觀

Format: Purified

儲存和穩定性

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

分析報告

Control
POSITIVE CONTROL: Conditioned, serum-free medium from (PMA-treated) rat fibrosarcoma cells or rat keratinocyte CCL-4.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable