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Key Documents

MAB1056

Sigma-Aldrich

Anti-Neutrophil Elastase Antibody, clone AHN-10

ascites fluid, clone AHN-10, Chemicon®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702

生物源

mouse

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

AHN-10, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... SERP1(27230)

特異性

Reacts specifically with human neutrophil elastase and not with the 3 homologous neutrophil neutral serine proteases, cathepsin G, esterase N and proteinase 3. Inhibits the elastinolytic activity of elastase. Elastase is felt to play an important role in a number of disease states.

應用

Anti-Neutrophil Elastase Antibody, clone AHN-10 detects level of Neutrophil Elastase & has been published & validated for use in IP, RIA & IC.
Immunoprecipitation

Immunocytochemistry

RIA

Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms

儲存和穩定性

Maintain in convenient aliquots at -20°C or colder for up to 12 months. Avoid thawing and refreezing.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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M Brittany Johnson et al.
Cellular microbiology, 17(5), 648-665 (2014-10-28)
During gonorrhoeal infection, there is a heterogeneous population of Neisseria gonorrhoeae (Gc) varied in their expression of opacity-associated (Opa) proteins. While Opa proteins are important for bacterial attachment and invasion of epithelial cells, Opa+ Gc has a survival defect after
Julia Mayerle et al.
Gastroenterology, 129(4), 1251-1267 (2005-10-19)
Cadherins play an important role in cell-cell contact formation at adherens junctions. During the course of acute pancreatitis, adherens junctions are known to dissociate-a requirement for the interstitial accumulation of fluid and inflammatory cells-but the underlying mechanism is unknown. Acute
The eicosanoid response to high dose UVR exposure of individuals prone and resistant to sunburn.
Anna Nicolaou,Mojgan Masoodi,Karl Gledhill,Ann Katarina Haylett,Anthony John Thody et al.
Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology null
Severely photosensitive psoriasis: a phenotypically defined patient subset.
Kirsty J Rutter,Rachel E B Watson,Lindsey F Cotterell,Thomas Brenn et al.
The Journal of Investigative Dermatology null
K M Skubitz et al.
Journal of leukocyte biology, 44(3), 158-165 (1988-09-01)
Neutrophil proteases are believed to play a role in the pathogenesis of a variety of human diseases. While many studies of proteases in models of disease have focused on elastase, neutrophils contain several proteases some of which share a high

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