推薦產品
生物源
mouse
品質等級
共軛
PE
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
AP20, monoclonal
物種活性
human
物種活性（以同源性預測）
bovine (immunogen homology)
製造商／商標名
Milli-Mark®
技術
flow cytometry: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... MAP2(4133)
一般說明
MAP-2 (microtubule associated protein-2) is one of several high molecular weight proteins that play an important role in brain neuron microtubule assembly. In addition to its association with microtubules, MAP-2 associates with neurofilaments and actin filaments suggesting that it may guide interaction among microtubules, other cytoskeletal elements, and cytoplasmic organelles. MAP-2 is a stringent marker for neurons. In addition, MAP-2 displays intracellular specificity. In the central nervous system, MAP-2 is confined to neuronal cell bodies and dendrites. There are exceptions, however, where some axons stain positive for small amounts of MAP-2. MAP-2 is uniformly distributed throughout the cell when first expressed in cultured neurons but becomes selectively localized as dendritic development proceeds. (Caceres, 1986; Dotti, 1987).
特異性
Antibody recognizes MAP-2.
免疫原
Recombinant Bovine brain microtubule protein.
應用
Milli-Mark Anti-MAP2-PE Antibody, clone AP20 is an antibody against MAP2 for use in FC.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
品質
Evaluated by flow cytometry using U251 cells
標靶描述
199.5 kDa Calculated
外觀
Protein A purified
Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
儲存和穩定性
Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.
分析報告
Control
U251 cells
U251 cells
法律資訊
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Zhijie Chen et al.
Cell death & disease, 13(5), 493-493 (2022-05-25)
Accumulating evidence supports the existence of glioma stem cells (GSCs) and their critical role in the resistance to conventional treatments for glioblastoma multiforme (GBM). Differentiation therapy represents a promising alternative strategy against GBM by forcing GSCs to exit the cell
Dong Woo Kang et al.
The Journal of pathology, 252(3), 304-316 (2020-07-30)
Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44High
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