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Key Documents

FCMAB203P

Sigma-Aldrich

Milli-Mark® Anti-CD64-PE Antibody, clone 10.1

clone 10.1, Milli-Mark®, from mouse

同義詞:

High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RIA, FcgammaRIa, Fc-gamma RI, FcRI

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.44

生物源

mouse

品質等級

共軛

PE

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

10.1, monoclonal

物種活性

human

製造商/商標名

Milli-Mark®

技術

flow cytometry: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FCGR1A(2209)

一般說明

CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).

特異性

Antibody recognizes Human CD64 antigen.

免疫原

Human rheumatoid synovial fluid cells and monocytes.

應用

Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

品質

Evaluated by flow cytometry using human PBMCs

標靶描述

72 kDa (Sun W, 1997)

外觀

Protein A purified
Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

儲存和穩定性

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

分析報告

Control
PBMC′s

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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