推薦產品
生物源
mouse
品質等級
共軛
FITC conjugate
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
SN3, monoclonal
物種活性
human
製造商／商標名
Milli-Mark®
技術
flow cytometry: suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CD24(100133941)
相關類別
一般說明
The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).
特異性
Antibody recognizes Human CD24 antigen.
免疫原
Isolated membrane fraction of the pre-B leukemic cell line NALM-1.
應用
Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
品質
Evaluated by flow cytometry using human PBMCs
標靶描述
35-45 kDa (Turni, 2002)
外觀
Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
儲存和穩定性
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
分析報告
Control
PBMCs
PBMCs
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Li Wang et al.
Experimental and therapeutic medicine, 14(5), 4773-4780 (2017-12-05)
Gemcitabine is the first-line chemotherapeutic agent for advanced adenocarcinoma of the pancreas, despite the high risk of chemoresistance as a major disadvantage. In the past few years, significant advances have been made in the field of pancreatic cancer stem-like cells
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