FCMAB110P
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate
clone 10H11.E12, from mouse, PE
同義詞:
A-T, mutated
AT mutated
TEL1, telomere maintenance 1, homolog
ataxia telangiectasia mutated
ataxia telangiectasia mutated (includes complementation groups A, C and D)
ataxia telangiectasia mutated protein
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About This Item
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一般說明
N-terminal c-Myc, GST-tagged, recombinant human Cardiac Troponin I full length, expressed by baculovirus in Sf21 insect cells. Purified using glutathione sepharose.
特異性
Antibody recognizes ATM phosphorylated at Ser1981.
Predicted to cross-react with rat based on sequence homology
免疫原
Epitope: Phosphorylated at and around Ser1981
KLH-conjugated, synthetic peptide corresponding to human ATM phosphorylated at Ser1981.
應用
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate detects level of phospho-ATM (Ser1981) & has been published & validated for use in FC.
品質
Evaluated by Flow Cytometry with HeLa cells.
標靶描述
~370 kDa Calculated
外觀
Purified mouse monoclonal IgG1κ conjugated to phycoerythrin in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.
分析報告
Control
Irradiated HeLa cells
Irradiated HeLa cells
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
International journal of radiation oncology, biology, physics, 84(3), 800-806 (2012-03-27)
We have previously shown that the antimalarial agent chloroquine can abrogate the lethal cellular effects of low-dose-rate (LDR) radiation in vitro, most likely by activating the ataxia-telangiectasia mutated (ATM) protein. Here, we demonstrate that chloroquine treatment also protects against lethal doses
Cancers, 12(9) (2020-09-16)
Resistance to chemotherapy by temozolomide (TMZ) is a major cause of glioblastoma (GBM) recurrence. So far, attempts to characterize factors that contribute to TMZ sensitivity have largely focused on protein-coding genes, and failed to provide effective therapeutic targets. Long noncoding
Stem cell research, 41, 101596-101596 (2019-11-02)
Using a Sendai Virus based vector delivering Yamanaka Factors, we generated induced Pluripotent Stem Cells (iPSCs) from peripheral blood mononuclear cells of a patient affected by Ataxia Telangiectasia (AT), caused by a novel homozygous deletion in ATM, spanning exons 5-7.
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