CBL412A5

Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor^™555 Conjugate

clone TU-20, from mouse, ALEXA FLUOR^™ 555

• 同義詞: Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 555
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: TU-20, monoclonal
• 物種活性: rat, pig
• 物種活性（以同源性預測）: primate (based on 100% sequence homology), bovine (based on 100% sequence homology), mouse (based on 100% sequence homology), porcine (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable
• 同型: IgG1
• NCBI登錄號: NP_001184110
• UniProt登錄號: Q13509
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Tubb3(22152)

描述

一般說明

Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

特異性

This antibody reacts with the C-terminus of the beta-III isoform of tubulin, which is known to be neuron specific. Does not identify beta tubulin found in glial cells.

免疫原

Epitope: C-terminus

Synthetic peptide corresponding to human Tubulin β-III.

應用

Detect Tubulin β-III using this Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor^™555 Conjugate validated for use in ICC.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

品質

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Tubulin β-III in rat E18 primary cortex cells.

標靶描述

The unconjugated parent antibody (Cat. No. MAB1637) has an observed molecular weight at ~55 kDa

外觀

Protein G Purified

Purified mouse monoclonal IgG1 conjugated to Alexa Fluor^™ 555 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

儲存和穩定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
Rat E18 primary cortex cells

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable