ABT272

Anti-SUN2 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: SUN domain-containing protein 2, Protein unc-84 homolog B, Rab5-interacting protein, Rab5IP, Sad1/unc-84 protein-like 2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse, human
• 技術: immunocytochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_001186508
• UniProt登錄號: Q9UH99
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SUN2(25777)

描述

一般說明

SUN domain-containing protein 2 (SUN2), or Protein UNC-84 homolog B (UNC84B), is a single-pass nuclear envelope transmembrane protein responsible for nuclear migrations that are essential for development. SUN2 has a predicted transmembrane domain and a C-terminal region with similarity to the S. pombe spindle pole body protein Sad1. SUN2 interacts with RAB5A and is widely expressed, and highly expressed in the heart, lungs and muscles. UNC-84 may function to facilitate a nuclear-centrosomal interaction required for nuclear migration and anchorage.

免疫原

Epitope: N-terminus

Linear peptide corresponding to the N-terminus of human Sun2.

應用

Detect SUN2 using this Anti-SUN2 antibody validated for use in western blotting & ICC.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Western Blotting Analysis: A 1:500 dilution from a representative lot detected SUN2 in 10 µg of A431, Jurkat, L6, and NIH/3T3 cell lysate.
Western Blotting Analysis: A representative lot detected SUN2 recombinant protein (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Immunocytochemistry Analysis: A representative lot detected SUN2 in human foreskin fibroblasts and NIH/3T3 cells (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).

品質

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected SUN2 in 10 µg of HEK293 cell lysate.

標靶描述

~ 78 kDa observed. Uncharacterized band(s) may appear in some lysates.

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable