ABN58

Anti-phospho MAP1B (Thr1265) Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Microtubule-associated protein 1B, MAP-1B, MAP1(X), MAP1.2, MAP1 light chain LC1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: rat
• 物種活性（以同源性預測）: mouse (immunogen homology)
• 技術: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: P14873
• 運輸包裝: wet ice
• 目標翻譯後修改: phosphorylation (pThr1265)
• 基因資訊: mouse ... Map1B(17755) ; rat ... Map1B(29456)

描述

一般說明

Microtubule-associated protein 1B (MAP1B) is neuron-specific and is thought to play a part in controlling the neuronal cytoskeleton. MAP1B is made up of heavy and light chains and is involved in the microtubule and actin filament association. MAP1B may have an important role in axon formation by supporting microtubule dynamics and controlling cytoskeletal arrangement. MAP1B has also been associated with Netrin 1 signaling.

特異性

Other homologies: Human (91% sequence homology).

This antibody recognizes MAP1B phosphorylated at Thr1265.

免疫原

Epitope: Phosphorylated Thr1265

KLH-conjugated linear peptide corresponding to mouse MAP1B phosphorylated at Thr1265.

應用

Anti-phospho MAP1B (Thr1265) Antibody is an antibody against phospho MAP1B (Thr1265) for use in WB, IH & IC.

Immunohistochemistry Analysis: 1:600 dilution from a representative lot detected MAP1B in embryonic (E12) rat spinal cord tissue. (Image courtesy of Dr. Phillip R. Gordon-Weeks, King′s College London.)

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)

品質

Evaluated by Western Blot in S1 rat brain tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.

標靶描述

~300 kDa observed

分析報告

Control
S1 rat brain tissue lysate

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable