ABN457

Anti-Peptide YY Antibody

from chicken, purified by affinity chromatography

• 同義詞: Peptide YY1, PYYPYY-I, Peptide tyrosine tyrosine, Peptide YY(3-36), PYY-II, Peptide YY
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: chicken
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: rat, mouse
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgY
• NCBI登錄號: NP_004151
• UniProt登錄號: P10082
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Pyy(217212) ; rat ... Pyy(287730)

描述

一般說明

Peptide YY (UniProt P10082; also known as Peptide tyrosine tyrosine, PYY, PYY-I) is encoded by the PYY (also known as PYY1) gene (Gene ID 5697) in human. Peptide YY is initially produced as a preproprotein with a signal and a propeptide sequence (aa 1-28 and aa 68-97, respectively). There are two major forms of mature peptide YY corresponding to aa 29-64 and aa 31-64 of the prepro sequence, commonly known as YY(1-36) and YY(3-36), respectively. PYY is one of several well recognized circulating anorexigenic peptides, whose productions increase post-prandially. PYY and glucagon-like peptide 1 (GLP-1) are released from L cells that predominate in the distal ileum and colon. The melanocortin-4 receptor (MC4R) is reported to mediate PYY and GLP-1 release from enteroendocrine L cells upon melanocortin peptides stimulation.

特異性

Reacts with prepro-, pro-, and mature peptide YY & peptide YY(3-36).

免疫原

Epitope: Mature Peptide YY

KLH-conjugated linear peptide corresponding to the mature human peptide YY.

應用

Anti-Peptide YY Antibody, Cat. No. ABN457, is a highly specific chicken Polyclonal antibody, that targets Peptide YY and has been tested in Western Blotting, Immunohistochemistry.

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peptide YY in rat colon tissue.

品質

Evaluated by Western Blotting in rat small intestine tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected Peptide YY in 10 µg of rat small intestine tissue lysate.

標靶描述

~11 kDa observed

其他說明

Concentration: Please refer to lot specific datasheet.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable