生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
技術
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ZEB1(6935)
一般說明
Zinc finger E-box-binding homeobox 1 (ZEB1), also known as Transcription factor 8 (TCF8), Negative regulator of IL2, and NIL-2-A zinc finger protein acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. ZEB1 has also been implicated in regulating the expression of ATP1A1, E-cadherin, BCL6, and RCOR1 genes. ZEB1 regulates neurogenesis and neuronal differentiation, but is also implicated in tumor formation. ZEB1 is expressed in heart and skeletal muscle. Mutations in ZEB1 have been associated with corneal dystrophy.
免疫原
KLH-conjugated linear peptide corresponding to human ZEB1 .
應用
Detect ZEB1 using this rabbit polyclonal antibody, Anti-ZEB1 Antibody validated for use in western blotting, ICC & Immunofluorescence.
Immunocytochemistry Analysis: 20 µg/mL from a representative lot detected ZEB1 in HeLa cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected ZEB1 in HeLa cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected ZEB1 in HeLa cells.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
品質
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ZEB1 in 15 µg of HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ZEB1 in 15 µg of HeLa cell lysate.
標靶描述
~130 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes two isoforms at ~124 kDa
外觀
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
HeLa cell lysate
HeLa cell lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Hong Chang et al.
Scientific reports, 6, 22312-22312 (2016-03-01)
MicroRNAs are small and non-coding RNA molecules with the master role in regulation of gene expression at post-transcriptional/translational levels. Many methods have been developed for microRNA loss-of-function study, such as antisense inhibitors and sponges; however, the robustness, specificity, and stability
Xin Yao et al.
Oncotarget, 8(42), 72235-72249 (2017-10-27)
The Transducin-like enhancer of split 1 (TLE1) corepressor protein is overexpressed in human lung tumors and is a putative lung-specific oncogene. However, the molecular mechanism underlying its oncogenic function remains to be delineated. Here, we report an important role of
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