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Merck
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Key Documents

ABD24

Sigma-Aldrich

Anti-Dermo-1 Antibody

from rabbit, purified by affinity chromatography

同義詞:

Twist-related protein 2, Class A basic helix-loop-helix protein 39, bHLHa39, Dermis-expressed protein 1, Dermo-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human, rat

物種活性(以同源性預測)

chicken (based on 100% sequence homology), mouse (based on 100% sequence homology)

技術

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... TWIST2(117581)

一般說明

Dermo-1, also known as Twist-related protein 2, is a basic helix-loop-helix transcription factor that has been shown to be a negative regulator for gene transcription and apoptosis. Basic helix-loop-helix transcription factors are implicated in cell lineage determination and differentiation. Dermo-1 shares extensive homology with another basic helix-loop-helix transcription factor, Twist. Studies suggest that Dermo-1 may inhibit osteoblast maturation during osteoblast development and maintain cells in preosteoblast phenotype.

免疫原

KLH-conjugated linear peptide corresponding to human Dermo-1.

應用

Anti-Dermo-1 Antibody is an antibody against Dermo-1 for use in WB, IH(P).
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Dermo-1 in rat liver tissue.
Research Category
Stem Cell Research
Research Sub Category
Transcription Factors

品質

Evaluated by Western Blot in rat liver tissue lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected Dermo-1 on 10 µg of rat liver tissue lysate.

標靶描述

~18 kDa observed

外觀

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Rat liver tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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