ABC348

Anti-Bmf Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Bcl-2-modifying factor, Bmf
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: Q96LC9
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BMF(90427)

描述

一般說明

Bcl-2-modifying factor (Bmf) is a member of the Bcl-2 family containing one BCL2 homology domain 3. Members of this family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell′s actin cytoskeleton. Bmf is constitutively expressed in many tissues. There are 3 isoforms of Bmf. Isoform 1 is mainly expressed in B-lymphoid cells while isoform 2 and 3 are mainly expressed in B-CLL and normal B-cells.

特異性

This antibody recognizes the N-terminus of Bmf.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human Bmf.

應用

Detect Bcl-2-modifying factor using this rabbit polyclonal antibody, Anti-Bmf Antibody validated for use in western blotting & IHC.

Immunocytochemistry Analysis: 10 µg/mL from a representative lot detected Bmf in HeLa cells.

品質

Evaluated by Western Blotting in HepG2 and HEK293 cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected Bmf in 15 µg of HepG2 and HEK293 cell lysates.

標靶描述

~25 kDa observed

分析報告

Control
HepG2 and HEK293 cell lysates

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable