推薦產品
生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse
製造商／商標名
Chemicon®
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Cyp2B10(13088)
一般說明
CYP2b10（细胞色素P450，家族2，亚家族b，多肽10）是单加氧酶的细胞色素P450超家族的成员，其催化涉及药物代谢和胆固醇，类固醇和其他脂质合成的许多反应。
特異性
AB9916对CYP2b10具有特异性。
免疫原
表位：AA I182 – T205
重组2b10
應用
该抗CYP2b10抗体经过验证可用于WB中检测CYP2b10。
品質
已通过免疫印迹进行常规评估。
標靶描述
58kDa
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Shinhee Park et al.
Acta pharmaceutica Sinica. B, 6(5), 475-491 (2016-10-07)
Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect in intestine. Sixty-day-old
Kentaro Nobutani et al.
Pharmacology research & perspectives, 5(5) (2017-10-04)
Herbal medicines and natural products used for maintenance of health or treatment of diseases have many biological effects, including altering the pharmacokinetics and metabolism of other medications. Daikenchuto (TU-100), an aqueous extract of ginger, ginseng, and Japanese green pepper fruit
Cindy Yanfei Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 153(2), 282-302 (2016-07-15)
Safety concerns have emerged regarding the potential long-lasting effects due to developmental exposure to xenobiotics. The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are critical xenobiotic-sensing nuclear receptors that are highly expressed in liver. The goal of this
Xia Wen et al.
The Journal of pharmacology and experimental therapeutics, 344(1), 244-252 (2012-10-12)
Phase II enzymes, including Ugts, Sults, and Gsts, are critical for the disposition and detoxification of endo- and xenobiotics. In this study, the mRNA and protein expression of major phase II enzymes, as well as key regulatory transcription factors, were
p53-mediated regulation of bile acid disposition attenuates cholic acid-induced cholestasis in mice.
Pan Chen et al.
British journal of pharmacology, 174(23), 4345-4361 (2017-09-15)
The tumour suppressor p53 is traditionally recognized as a surveillance molecule to preserve genome integrity. Recent studies have demonstrated that it contributes to metabolic diseases. Here, we investigated the role of p53 in the regulation of bile acid disposition and
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