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Merck
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Key Documents

AB9040

Sigma-Aldrich

Anti-Nerve Growth Factor Antibody, pro

serum, Chemicon®

同義詞:

proNGF

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, human, mouse

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... NTF3(4908)

特異性

Reacts with proNGF.

免疫原

Recombinant protein from mouse proNGF.

應用

Anti-Nerve Growth Factor Antibody, pro is an antibody against Nerve Growth Factor for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Western blot: 1:250-1:500. Reacts with bands of 30 kD and 32 kD.

Immunohistochemistry: 1:250 on frozen sections.

Immunocytochemistry

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

外觀

Rabbit serum. Liquid.

儲存和穩定性

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Bernadette Rogez et al.
Veterinary pathology, 57(4), 507-519 (2020-05-01)
Accumulating data highlight the role of neurotrophins and their receptors in human breast cancer. This family includes nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), both synthetized as proneurotrophins (proNGF and proBDNF). (pro)NGF and (pro)BDNF initiate their biological effects
Sam Faulkner et al.
Oncotarget, 7(19), 28488-28497 (2016-04-14)
The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to define the clinicopathological significance of proNGF in thyroid cancer. ProNGF expression was analysed by immunohistochemistry in two
Sam Faulkner et al.
FASEB bioAdvances, 2(7), 398-408 (2020-07-18)
Nerve growth factor (NGF) and its receptors are increasingly implicated in cancer progression, but their expression in cervical cancer is unclear. The objective of this study was to define the protein expression of NGF, its precursor (proNGF), as well as
Yohann Demont et al.
The Journal of biological chemistry, 287(3), 1923-1931 (2011-12-01)
The precursor of nerve growth factor (proNGF) has been described as a biologically active polypeptide able to induce apoptosis in neuronal cells, via the neurotrophin receptor p75(NTR) and the sortilin receptor. Herein, it is shown that proNGF is produced and
Mariano Catanesi et al.
Cell biology international, 44(8), 1734-1744 (2020-04-29)
Alzheimer's disease represents the most prevalent neurodegeneration worldwide, clinically characterized by cognitive and memory impairment. New therapeutic approaches are extremely important to counteract this disorder. This research is focused on the potential use of choline alfoscerate in preventing neuronal death

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