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重要文件

AB3572P

Sigma-Aldrich

Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular

Chemicon®, from rabbit

同義詞:

oatp2, OATP-B1, Brain digoxin carrier protein

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat

製造商/商標名

Chemicon®

技術

ELISA: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

一般說明

Organic Anion Transporting Polypeptide 2 is an integral membrane protein that mediates the sodium-independent transport of organic ions, cardiac glycosides and thyroid hormones. Oatp2 is highly expressed in brain, liver, and kidney but not expressed in heart, spleen, lung, skeletal muscle, or testis.

特異性

Recognizes rat Organic Ion Transporter 2 Polypeptide 2.

免疫原

A 12 amino acid peptide sequence near the cytoplasmic, C-terminus of rat OATP2. The immunogen shows no significant sequence similarity to other OATPs or other proteins.

應用

Detect Organic Anion Transporting Polypeptide 2 using this Anti-Organic Anion Transporting Polypeptide 2 Antibody, C-terminus, intracellular validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. Rat OATP2 is approximately 75 kD in brain and liver (Noe et al. 1997).

ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well.

Optimal working dilutions must be determined by the end user.

外觀

Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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T Abe et al.
The Journal of biological chemistry, 273(35), 22395-22401 (1998-08-26)
Two complementary DNAs for the organic anion transporter subtypes oatp2 and oatp3, which transport thyroid hormones as well as taurocholate, were isolated from a rat retina cDNA library. The sequence of oatp2 is identical to that recently reported (Noé, B.
M Kakyo et al.
FEBS letters, 445(2-3), 343-346 (1999-03-27)
The rabbit polyclonal antibody against rat organic anion transporting polypeptide 2 (oatp2) was raised and immunoaffinity-purified. Western blot analysis for oatp2 detected two bands ( 74 and 76 kDa) in rat brain and a single band (76 kDa) in the
Camilla A Thorling et al.
Journal of biomedical optics, 18(10), 101306-101306 (2013-07-03)
The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury is a common occurrence in liver surgery, and the developing oxidative stress can lead to graft failure. We used intravital
Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats.
Johnson, BM; Zhang, P; Schuetz, JD; Brouwer, KL
Drug Metabolism and Disposition null

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