推薦產品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
rat
製造商/商標名
Chemicon®
技術
ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
rat ... Slco1A4(170698)
一般說明
Organic Anion Transporting Polypeptide 2 is an integral membrane protein that mediates the sodium-independent transport of organic ions, cardiac glycosides and thyroid hormones. Oatp2 is highly expressed in brain, liver, and kidney but not expressed in heart, spleen, lung, skeletal muscle, or testis.
特異性
Recognizes rat Organic Ion Transporter 2 Polypeptide 2.
免疫原
A 12 amino acid peptide sequence near the cytoplasmic, C-terminus of rat OATP2. The immunogen shows no significant sequence similarity to other OATPs or other proteins.
應用
Detect Organic Anion Transporting Polypeptide 2 using this Anti-Organic Anion Transporting Polypeptide 2 Antibody, C-terminus, intracellular validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. Rat OATP2 is approximately 75 kD in brain and liver (Noe et al. 1997).
ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
外觀
Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
T Abe et al.
The Journal of biological chemistry, 273(35), 22395-22401 (1998-08-26)
Two complementary DNAs for the organic anion transporter subtypes oatp2 and oatp3, which transport thyroid hormones as well as taurocholate, were isolated from a rat retina cDNA library. The sequence of oatp2 is identical to that recently reported (Noé, B.
M Kakyo et al.
FEBS letters, 445(2-3), 343-346 (1999-03-27)
The rabbit polyclonal antibody against rat organic anion transporting polypeptide 2 (oatp2) was raised and immunoaffinity-purified. Western blot analysis for oatp2 detected two bands ( 74 and 76 kDa) in rat brain and a single band (76 kDa) in the
Camilla A Thorling et al.
Journal of biomedical optics, 18(10), 101306-101306 (2013-07-03)
The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury is a common occurrence in liver surgery, and the developing oxidative stress can lead to graft failure. We used intravital
Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats.
Johnson, BM; Zhang, P; Schuetz, JD; Brouwer, KL
Drug Metabolism and Disposition null
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