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重要文件

AB1570W

Sigma-Aldrich

Anti-GABA Transporter-1 Antibody

Chemicon®, from rabbit

同義詞:

GAT-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
polyclonal
application:
IHC
WB
物種活性:
rabbit, mouse, monkey, human, rat, feline
技術:
immunohistochemistry: suitable
western blot: suitable
citations:
9

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rabbit, mouse, monkey, human, rat, feline

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SLC6A1(6529)

特異性

Recognizes GABA Transporter-1 (GAT-1), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.

免疫原

Rat GAT-1, C-terminus (aa 588-599)

應用

Anti-GABA Transporter-1 Antibody detects level of GABA Transporter-1 & has been published & validated for use in IH & WB.
Western blotting: 1:200-1:500 (67 kDa)

Immunohistochemistry

Optimal working dilutions must be determined by the end user.

標靶描述

67 kDa

外觀

Affinity Purified antibody. Lyophilized from 0.1 M PBS with 1% BSA and 0.1% sodium azide. Reconstitute with 100 μL of sterile distilled water.

儲存和穩定性

Maintain lyophilized material at 2–8°C for up to 12 months. Maintain reconstituted materialat -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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象形圖

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訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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存取文件庫

Substrate-mediated regulation of gamma-aminobutyric acid transporter 1 in rat brain.
Jia Hu,Michael W Quick
Neuropharmacology null
Brain-derived neurotrophic factor (BDNF) enhances GABA transport by modulating the trafficking of GABA transporter-1 (GAT-1) from the plasma membrane of rat cortical astrocytes.
Vaz, SH; J?rgensen, TN; Cristov?o-Ferreira, S; Duflot, S; Ribeiro, JA; Gether, U; Sebasti?o, AM
The Journal of Biological Chemistry null
GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET.
FJ Moss, PI Imoukhuede, K Scott, J Hu, JL Jankowsky, MW Quick, HA Lester
The Journal of General Physiology null
C E Ribak et al.
The Journal of comparative neurology, 367(4), 595-606 (1996-04-15)
This study evaluates the distribution of two high affinity gamma-aminobutyric acid (GABA) transporters (GAT-1 and GAT-3) in the rat hippocampus using immunocytochemistry and affinity purified antibodies. GAT-1 immunoreactivity was prominent in punctate structures and axons in all layers of the
F Conti et al.
The Journal of comparative neurology, 396(1), 51-63 (1998-06-12)
High-affinity gamma-aminobutyric (GABA) plasma membrane transporters (GATs) influence the action of GABA, the main inhibitory neurotransmitter in the human cerebral cortex. In this study, the cellular expression of GAT-1, the main cortical GABA transporter, was investigated in the human cerebral

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