8.56057

H-Pro-2-ClTrt resin

Novabiochem^®

• 同義詞: Chlorotrityl Resin
• 分類程式碼代碼: 12352209
• NACRES: NA.22

屬性

• 品質等級: 400
• 產品線: Novabiochem^®
• 形狀: beads
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 儲存溫度: 2-8°C

描述

一般說明

Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal proline amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in DCM. The use of this resin enables the synthesis of peptides containing C-terminal Pro without risk of diketopiperazine formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

應用

• B Yakimova et al. Reported the use of H-Pro-2-ClTrt resin in the synthesis of short peptides with potential ACE inhibitory activity (B Yakimova, et al., 2021).
• S Wang et al. Detailed the use of H-Pro-2-ClTrt resin in a study on aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase (S Wang, et al., 2022).
• LP Vu et al. Described the use of H-Pro-2-ClTrt resin in the synthesis of inhibitors for serine proteases (LP Vu, et al., 2022).

聯結

Replaces: 04-12-2805

分析報告

Color (visual): pale yellow to beige
Appearance of substance (visual): beads
Identity (of the substitution): passes test
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific value
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable