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Key Documents

8.55063

Sigma-Aldrich

NovaSyn TG bromo resin

Novabiochem®

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About This Item

分類程式碼代碼:
12352101
NACRES:
NA.22

品質等級

產品線

NovaSyn® TG
Novabiochem®

形狀

beads

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

應用

peptide synthesis

儲存溫度

2-8°C

一般說明

NovaSyn TG bromo resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol [1,2,3], in which the ends of the PEG chains have been bromo functionalized. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis. This support may be used for the immobilization of alcohols, carboxylic acids, phenols and thiols, or as base support for other linkers [4,5]. Loading of this support can be carried out using the same methods as those previously described for Merrifield resin.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
[4] K. H. Gordon & S. Balasubramanian (2001) Org. Lett., 3, 53.
[5] D. Tumelty, et al. (2001) Org. Lett., 3, 83

聯結

Replaces: 01-64-0095

分析報告

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemntal analysis of bromine): 0.20 - 0.40 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result

法律資訊

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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