8.52204

Fmoc-Glu(OBzl)-OH

Novabiochem^®

• 同義詞: Fmoc-Glu(OBzl)-OH, N-α-Fmoc-L-glutamic acid γ-benzyl ester
• 經驗公式（希爾表示法）: C₂₇H₂₅NO₆
• CAS號碼: 123639-61-2
• 分子量：: 459.49
• MDL號碼: MFCD00065642
• 分類程式碼代碼: 12352209
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥96.0% (acidimetric); ≥97.0% (HPLC); ≥98% (TLC)
• 形狀: powder
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• mp: 70 °C (decomposition)
• 應用: peptide synthesis
• 官能基: carboxylic acid
• 儲存溫度: 2-30°C
• InChI: 1S/C27H25NO6/c29-25(33-16-18-8-2-1-3-9-18)15-14-24(26(30)31)28-27(32)34-17-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,23-24H,14-17H2,(H,28,32)(H,30,31)/t24-/m0/s1
• InChI 密鑰: HJJURMMMGPQIQP-DEOSSOPVSA-N

描述

一般說明

Building block for introduction of glutamic acid bearing TFA-labile benzyl ester side-chain protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA. Prone to pyroglutamate formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

聯結

Replaces: 04-12-1019

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 2.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable