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Key Documents

8.51072

Sigma-Aldrich

6-Carboxyfluorescein

Novabiochem®

同義詞:

6-Carboxyfluorescein, 6-FAM

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About This Item

經驗公式(希爾表示法):
C21H12O7
CAS號碼:
分子量::
376.32
MDL號碼:
分類程式碼代碼:
12352005
NACRES:
NA.22

品質等級

產品線

Novabiochem®

化驗

≥95% (TLC)
≥98.0% (HPLC)

形狀

powder

反應適用性

reagent type: fluorescent-labelling reagent

製造商/商標名

Novabiochem®

應用

peptide synthesis

儲存溫度

2-8°C

InChI

1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25)

InChI 密鑰

BZTDTCNHAFUJOG-UHFFFAOYSA-N

一般說明

This high purity fluorescent dye (λem494 nm, λex 518 nm) is supplied as a single isomer, which ensures production of labeled products of defined chemical structure, as well as greatly simplifying purification and characterization. FAM should be introduced as the last step in the synthesis to avoid formation of side-products, or protected by tritylation prior to acylation or hydrazine treatment [1].

Literature references

[1] R. Fischer, et al. (2003) Bioconjugate Chem., 14, 653.

聯結

Replaces: 01-63-0113

分析報告

Color (visual): yellow to orange
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC (EtOAc/MeOH/H2O/DIPEA 60 : 30 : 10 : 3)): ≥ 95 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

The spectral properties of Novabiochem®’s chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry. Novabiochem® range offers one of the most extensive ranges of labeling reagents for the synthesis of such peptides, including the unique NovaTag™ resins for the production of C-terminally-labeled peptide

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