8.40124

Span^® 85

for synthesis

• 同義詞: Span^® 85
• 經驗公式（希爾表示法）: C₆₀H₁₀₈O₈
• CAS號碼: 26266-58-0
• 分子量：: 957.49
• MDL號碼: MFCD00133820
• 分類程式碼代碼: 12352108
• 酶委員會索引編號: 247-569-3
• NACRES: NA.22

屬性

• 蒸汽壓力: <1.4 hPa ( 20 °C)
• 品質等級: 200
• 形狀: liquid
• 效力: 39800 mg/kg LD₅₀, oral (Rat)
• 運動黏度: 120 cSt(40 °C)
• 轉變溫度: flash point 225 °C
• 溶解度: insoluble <0.001 g/L
• 密度: 0.95 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-/t54-,55?,59+,60-/m1/s1
• InChI 密鑰: PRXRUNOAOLTIEF-XDTJCZEISA-N

描述

應用

• Macromolecular Stabilization: Span^® 85 is used as a stabilizer for the preparation of PMMA colloidal particles in nonpolar media, proving effective in maintaining stability under various conditions, crucial for industrial applications in coatings and advanced materials manufacturing (Liu et al., 2022).


• Enhanced Nanoemulsion Systems: It plays a critical role in the formation of aerosolized nanoemulsion systems encapsulating docetaxel and curcumin, utilized in cancer therapy to improve therapeutic outcomes through enhanced drug delivery mechanisms (Abdul Rahman et al., 2020).


• Skin Protection Formulations: Span^® 85 is integral in the formulation and clinical assessment of microemulsion-based hydrogels for UV protection, demonstrating its utility in skincare products by enhancing sun protection factor and skin compatibility (Ebrahimi et al., 2019).


• Transdermal Drug Delivery: This surfactant is utilized in tailoring novel soft nano-vesicles, known as ′Flexosomes′, to enhance transdermal drug delivery, which is pivotal for non-invasive therapeutic applications and improving patient compliance (Mansour et al., 2019).

分析報告

羟值：55 - 75
皂化值：170 - 190
鉴别（IR）：符合检验
由于其特定的熔程，产物可以是固体、液体、固化熔体或过冷熔体。

法律資訊

Span is a registered trademark of Croda International PLC

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 437.0 °F
• 閃點（°C）: 225 °C