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Key Documents

662047

Sigma-Aldrich

Anti-Uncoupling Protein-2 (UCP-2) (144-157) Rabbit pAb

liquid, Calbiochem®

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

包含

0.1% sodium azide as preservative

物種活性

human, mouse, rat

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG

運輸包裝

wet ice

儲存溫度

−70°C

目標翻譯後修改

unmodified

基因資訊

human ... UCP2(7351)

一般說明

Protein A purified rabbit polyclonal antibody. Recognizes the UCP-2 protein.
Recognizes the UCP-2 protein.

免疫原

a synthetic peptide [(C)QARAGGGRRYQSTV] corresponding to amino acids 144-157 of human and mouse UCP-2

應用

ELISA (1:100,000)

Immunoblotting (1:1000)

Immunocytochemistry (1:500)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

其他說明

Does not react with UCP-1 or UCP-3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Stuart, J.A., et al. 2001. J. Biol. Chem.276, 18633.
Gimeno, R.E., et al. 1997. Diabetes46, 900.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jay D Turner et al.
Circulation research, 106(4), 730-738 (2010-01-09)
Uncoupling protein (UCP)2 is a mitochondrial inner membrane protein that is expressed in mammalian myocardium under normal conditions and upregulated in pathological states such as heart failure. UCP2 is thought to protect cardiomyocytes against oxidative stress by dissipating the mitochondrial
P Brauner et al.
Pediatric research, 49(3), 440-447 (2001-03-03)
Hepatic hematopoiesis is prominent during fetal life and ceases around birth. In rodent liver, the decline of the hepatic hematopoiesis starts abruptly at birth being accompanied by a decrease of mitochondrial uncoupling protein 2 (UCP2) expression in monocytes/macrophages, whereas hepatocytes
Anjum Dihingia et al.
Scientific reports, 8(1), 10021-10021 (2018-07-04)
This study for the first time examined the prophylactic role of Tungrymbai, a well-known fermented soybean food of North-East India, against hepatic steatosis. Treatment with hexane-isopropanolic (2:1, HIET) but not hydro-alcoholic (70% ethanol, HAET) extract dose-dependently (0.1, 0.2, or 0.3 µg/mL)
Jong-Seok Moon et al.
The Journal of clinical investigation, 125(2), 665-680 (2015-01-13)
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1-dependent maturation and secretion of proinflammatory

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