572631

SU5402

InSolution, ≥95%, Inhibits the tyrosine kinase activity of FGFR1

• 同義詞: InSolution SU5402
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic); protect from light
• 儲存溫度: −70°C

描述

一般說明

Inhibits the tyrosine kinase activity of FGFR1 (IC₅₀ = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC₅₀ = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

外觀

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Mohammadi, M., et al. 1997. Science 276, 955.

法律資訊

Not available for sale in the United States.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 188.6 °F - (refers to pure substance)
• 閃點（°C）: 87 °C - (refers to pure substance)