561300

E-Selectin, Human, Recombinant, CHO Cells

• 同義詞: CD62E, ELAM-1
• 分類程式碼代碼: 12352202

屬性

• 化驗: ≥95% (SDS-PAGE)
• 品質等級: 100
• 形狀: lyophilized
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 雜質: <1 EU/μg Endotoxin (EU/μg of E-Selectin)
• 運輸包裝: wet ice
• 儲存溫度: −20°C

描述

一般說明

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

生化／生理作用

Shown to bind to E-selectin ligands on U937 cells.

警告

Toxicity: Standard Handling (A)

外觀

Lyophilized from Dulbecco′s PBS with stabilizer.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute to 1 mg/ml with sterile H₂O.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1