524736

Phosphodiesterase 4B2, His•Tag^®, Human, Recombinant, S. frugiperda

• 同義詞: PDE4B2, cAMP-Specific Phosphodiesterase 4B2
• 分類程式碼代碼: 12352202
• NACRES: NA.54

屬性

• 重組細胞: expressed in baculovirus infected Spodoptera frugiperda cells
• 品質等級: 100
• 形狀: liquid
• 比活性: ≥0.25 U/μL
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 運輸包裝: wet ice
• 儲存溫度: −70°C

描述

一般說明

Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.

警告

Toxicity: Standard Handling (A)

單位定義

One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.

外觀

In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Smith, P.G., et al. 2005 Blood105, 308.
Baroja, M.L., et al. 1999. J. Immunol.162, 2016.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable