442630-M

GMBS

• 同義詞: GMBS, N-γ-Maleimidobutyryloxysuccinimide
• 經驗公式（希爾表示法）: C₁₂H₁₂N₂O₆
• CAS號碼: 80307-12-6
• 分子量：: 280.23
• MDL號碼: MFCD00036817
• 分類程式碼代碼: 12161500
• NACRES: NA.24

屬性

• 化驗: ≥90% (HPLC)
• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 儲存溫度: −20°C
• InChI: 1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
• InChI 密鑰: PVGATNRYUYNBHO-UHFFFAOYSA-N

描述

一般說明

Heterobifunctional reagent useful for preparation of conjugates such as secondary antibodies and β-galactosidase for EIA procedures or for immobilizing enzymes on solid supports.

N-γ-maleimidobutyryloxysuccinimide ester (GMBS) is an aliphatic crosslinker for immunotoxins (IT).(1) It is used for the generation of conjugated Poly-γ-D-glutamic acid.

應用

GMBS is suitable for use:

• as a hetero-bifunctional cross-linking reagent for the immobilization of neural adhesion molecule L1 onto silicon dioxide surface
• for the crosslinking of biochips with functionalized gold nanoparticles
• for coating salinized capillary tube prior to neutravidin treatment in biosensor sandwich immunoassay

警告

Toxicity: Irritant (B)

重構

Reconstitute to 10 mg/ml in tetrahydrofuran or DMSO. Add 1 ml of this stock solution dropwise, with stirring, to 10 ml of 20 mM phosphate buffer.

其他說明

Rusin, K.M., et al. 1992. Biosens. Bioelectron. 7, 367.
Kitagawa, T., et al. 1983. J. Biochem. 94, 1160.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable