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Merck
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重要文件

437620

Sigma-Aldrich

Lipopolysaccharide, E. coli J5

Mutant of E. coli O111: B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.77

品質等級

形狀

lyophilized

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

雜質

<2.5% Protein
5.0-10.0% 2-keto-3-deoxyoctonate (KDO)

溶解度

water: 1 mg/mL

負離子痕跡

phosphate (PO43-): 6.0-15.0%

運輸包裝

ambient

儲存溫度

2-8°C

一般說明

Mutant of E. coli 0111:B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Highly purified preparation.
Mutant of E. coli O111: B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.

生化/生理作用

Cell permeable: no
Primary Target
Inducible nitric oxide synthase
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Harmful (C)

準備報告

LPS will form a suspension in H₂O; slight warming and vortexing may be required to achieve complete dispersion in H₂O. Addition of 0.5% triethylamine will also help with dispersion; triethylamine is very basic and can be neutralized with Trix-HCl to avoid hydrolysis of the fatty acid chains.

重構

Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 1 year at 4°C.

其他說明

Hattori, S., et al. 1995. Biochem. Mol. Biol. Int.35, 177.
Mayeux, P.R., et al. 1995. Biochem. Pharmacol.49, 115.
Norimatsu, M., et al. 1995. Infect. Immun.63, 1122.
Feinstein, D.L., et al. 1993. J. Neurochem.60, 1945.
Zhang, Y.H., et al. 1993. Infect. Immun.61, 5044.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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