420291

IPTG，无动物源性成分，高纯度

Inducer of β-D-galactosidase. Used in the stimulation of β-galactosidase in cellular systems in which dioxane would disrupt normal cell function. Contains no animal-derived products.

• 同義詞: IPTG，无动物源性成分，高纯度, 异丙基-β-D-硫代吡喃半乳糖苷
• 經驗公式（希爾表示法）: C₉H₁₈O₅S
• CAS號碼: 367-93-1
• 分子量：: 238.30
• MDL號碼: MFCD00063273
• 分類程式碼代碼: 12352201
• NACRES: NA.25

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 雜質: Dioxane, none detected
• 顏色: white to off-white
• 溶解度: water: 100 mg/mL; methanol: soluble
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C9H18O5S/c1-4(2)15-9-8(13)7(12)6(11)5(3-10)14-9/h4-13H,3H2,1-2H3/t5-,6+,7+,8-,9+/m1/s1
• InChI 密鑰: BPHPUYQFMNQIOC-NXRLNHOXSA-N

描述

一般說明

β-D-半乳糖苷酶的诱导剂。在二恶烷会破坏正常细胞功能的细胞系统中用于刺激 β-半乳糖苷酶。不含动物源性产品。

應用

• Mobile-CRISPRi as a powerful tool for modulating Vibrio gene expression.: This article explores the use of Mobile-CRISPRi for targeted gene regulation in Vibrio species, highlighting potential applications in microbial genetics and biotechnological innovations, including the manipulation of gene expression pathways facilitated by IPTG-induced systems (Geyman et al., 2024).


• A new Zymomonas mobilis platform strain for the efficient production of chemicals.: This research describes the development of a Zymomonas mobilis strain engineered for enhanced chemical production, utilizing IPTG for controlled expression of metabolic pathways, showcasing significant implications for biofuel production and industrial biotechnology (Frohwitter et al., 2024).


• Biophysical characterization and insights into the oligomeric nature of CD2-associated protein.: The study provides a detailed biophysical analysis of CD2-associated protein, employing IPTG-induced expression to elucidate its oligomeric structure and function in cellular signaling, offering insights into therapeutic target development (Qadri et al., 2024).


• Effective delivery of anti-PD-L1 siRNA with human heavy chain ferritin (HFn) in acute myeloid leukemia cell lines.: This research utilizes IPTG-inducible systems to study the delivery of therapeutic siRNAs in leukemia treatment, demonstrating the potential of IPTG in enhancing the efficacy of gene therapy approaches in oncology (Rajabinejad et al., 2024).


• Heterologous expression of nattokinase in E. coli: Biochemical characterization and functional analysis of fibrin binding residues.: This article details the heterologous expression of nattokinase in E. coli, facilitated by IPTG induction, focusing on its potential applications in thrombolytic therapy and its biochemical properties relevant to medical biochemistry (Jain et al., 2024).

警告

毒性：标准处理（A）

重構

复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多6个月。

其他說明

Lama, J., et al. 1992.Gene117, 185.
Zhang, Y., and Moss, B. 1991.Natl.Acad.Sci. USA88, 1511.
Rodriquez, J.F., and Smith, G.L.1990.Nucleic Acids Res.18, 5347.
Date, T., et al. 1988.Biochem.Biophys.Res. Commun.151, 598.
Lee, S.G., et al. 1988.Biochemistry27, 2983.
Cho, S., et al. 1985.Biochem.Biophys.Res. Commun.128, 1268.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable