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Key Documents

407137

Sigma-Aldrich

D-myo-Inositol 1,4,5-Trisphosphate, trisodium salt

≥95% (TLC), solid, second messenger involved in Ca2+ mobilization, Calbiochem®

同義詞:

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, D-Ins(1,4,5)P₃, 3Na

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About This Item

經驗公式(希爾表示法):
C6H12O15P3 · 3Na
CAS號碼:
分子量::
486.04
分類程式碼代碼:
12352211
NACRES:
NA.77

product name

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, Sodium salt of D-Ins(1,4,5)P₃ that has similar biological properties as the lithium salt.

品質等級

化驗

≥95% (TLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated (hygroscopic)

顏色

white

溶解度

water: 10 mg/mL

運輸包裝

ambient

儲存溫度

−20°C

InChI

1S/C6H15O15P3.6Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;;;;/q;6*+1/p-6/t1-,2+,3+,4-,5-,6-;;;;;;/m1....../s1

InChI 密鑰

MLMBGBMAFNSCOW-PPKFVSOLSA-H

相關類別

一般說明

Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).
Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).

生化/生理作用

Cell permeable: no
Primary Target
Mobilization of Ca2+ from intracellular stores.
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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Ka-Chun Mok et al.
Clinical and translational medicine, 11(11), e578-e578 (2021-11-30)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are members of the voltage-gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel-blocker, is FDA-approved for clinical use as a heart rate-reducing agent.

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