368059-M

Granzyme B Substrate II, Fluorogenic

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.

• 同義詞: Granzyme B Substrate II, Fluorogenic, Z-IETD-AFC, Caspase-8 Substrate II
• 經驗公式（希爾表示法）: C₃₇H₄₂F₃N₅O₁₃
• 分子量：: 821.75
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white
• 溶解度: DMSO: 1 mg/mL
• 螢光: λ_ex ~400 nm; λ_em ~505 nm
• 儲存溫度: −20°C

描述

一般說明

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.

A fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).

生化／生理作用

Primary Target
Fluorogenic substrate for the detection of granzyme B and caspase-8 activity

警告

Toxicity: Standard Handling (A)

序列

Z-Ile-Glu-Thr-Asp-AFC

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable