344215

Formononetin

A phytoestrogenic isoflavone found in soy-based foods.

• 同義詞: Formononetin, 7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
• 經驗公式（希爾表示法）: C₁₆H₁₂O₄
• CAS號碼: 485-72-3
• 分子量：: 268.26
• MDL號碼: MFCD00016948
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 描述: Merck USA index - 14, 4244
• 化驗: ≥90% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white to off-white
• 溶解度: methanol: 2 mg/mL; DMSO: 200 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O1c2c(ccc(c2)O)C(=O)C(=C1)c3ccc(cc3)OC
• InChI: 1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
• InChI 密鑰: HKQYGTCOTHHOMP-UHFFFAOYSA-N

描述

一般說明

A non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.

A phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.

生化／生理作用

Cell permeable: no

Primary Target
Selective inhibitor of the γ-isoform of alcohol dehydrogenase

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

重構

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.

其他說明

Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable