推薦產品
產品名稱
佛波醇12-十四酸酯13-乙酸酯，1MG,
形狀
solid
品質等級
製造商／商標名
Upstate®
技術
activity assay: suitable (kinase)
運輸包裝
wet ice
一般說明
光稳定剂12-肉豆蔻酸 13-乙酸酯（PMA）取自未熟的乌桕果实。它是一种促炎剂 。PMA通过释放细胞因子、烟酰胺腺嘌呤二核苷酸磷酯（NADPH）氧化酶和蛋白酶来产生作用，从而导致组织损伤或激活组胺的产生。这会促进血管重塑、发热和发红。PMA具有抗菌、增殖、抗增生和抗肿瘤作用。
應用
佛波醇12-肉豆蔻酸酯13-乙酸酯可用作单核细胞系如 U937 和THP-1细胞分化的诱导剂。
生化／生理作用
佛波醇12-肉豆蔻酸酯13-乙酸酯是一种促肿瘤佛波酯。它通过激活蛋白激酶C（PKC）信号途径来调节各种过程，如基因转录、细胞生长和分化、凋亡、免疫反应和受体脱敏。它促进人单核细胞THP-1细胞分化为功能性巨噬细胞。
外觀
C36H56O8
儲存和穩定性
在-20°C下可保存2年
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
訊號詞
Danger
危險分類
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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