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一般說明
肌肉RAS癌基因同源物（MRAS）在心血管疾病中起关键作用。该MRAS基因编码GTP结合蛋白的ras超家族的一员。MRAS存在于所有组织中，特别是心血管系统中。它参与信号转导，包括细胞生长和分化。
包裝
试剂盒容量：30次测定
成分
Ras检测试剂（Raf-1 RBD，琼脂糖）（目录号14-278）
Anti-Ras，克隆RAS10（目录号05-516）
100X GTPγS，10mM（目录号20-176）
100X GDP，100mM（目录号20-177）
Mg2+裂解/洗涤缓冲液，5X（目录号20-168）
Anti-Ras，克隆RAS10（目录号05-516）
100X GTPγS，10mM（目录号20-176）
100X GDP，100mM（目录号20-177）
Mg2+裂解/洗涤缓冲液，5X（目录号20-168）
品質
该试剂盒从已装有GTPγS的HeLa细胞裂解物中沉淀出Ras-GTP。使用1 μg/ml抗Ras克隆RAS10通过蛋白质免疫印迹检测沉淀的Ras-GTP
聯結
替代：SGT435
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
訊號詞
Danger
危險聲明
危險分類
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
儲存類別代碼
10 - Combustible liquids
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras.
Fu-Ming Tsai et al.
Cellular signalling, 18(3), 349-358 (2005-07-12)
The retinoid-inducible gene 1 (RIG1) protein is a retinoid-inducible growth regulator. Previous studies have shown that the RIG1 protein inhibits the signaling pathways of Ras/mitogen-activated protein kinases. However, neither the mode of action nor the site of inhibition of RIG1
Michael R Bennett et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(18), 7207-7217 (2003-08-09)
Neurofibromatosis type 1 (NF1) patients are predisposed to learning disabilities, macrocephaly, and brain tumors as well as abnormalities on magnetic resonance imaging that are postulated to result from abnormal myelination. Here we show that Nf1+/- spinal cords in adult mice
Richard J Calvert et al.
Analytical biochemistry, 343(2), 283-292 (2005-07-16)
Accurate measurement of activity of wild-type K-ras protein is important due to its tumor suppressor action in tissues such as lung. A published method by Taylor and co-workers uses plasmid-containing Escherichia coli cells to produce a glutathione-S-transferase/raf-1 ras binding domain
Fu-Ming Tsai et al.
Cellular signalling, 19(5), 989-999 (2007-01-02)
Retinoid-inducible gene 1 encodes RIG1 is a growth regulator, which inhibits the pathways of the RAS/mitogen-activated protein kinases by suppressing the activation of RAS. Confocal microscopic analysis demonstrated that RIG1 is localized in the endoplasmic reticulum (ER) and Golgi apparatus
Shin-ichiro Miura et al.
Biochemical and biophysical research communications, 306(4), 924-929 (2003-06-25)
Since we recently reported that high density lipoprotein, which contains the bioactive lipid sphingosine-1-phosphate (S1P) [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], induced human coronary artery endothelial cell (HCEC) tube formation mediated by a Ras/Raf/ERK (extracellular signal-activated kinase) pathway, we
文章
probiotics-and-human
Today, diverse studies report the benefits of probiotics, such as inhibitory effects on pathogens, aid in the management or prevention of chronic intestinal inflammatory diseases or atopic syndromes, and support to the immune system. Potential beneficial applications abound, researchers continue to evaluate the effictiveness and clarify the mechanisms of action of probiotics.
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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