14-700

NEK11 Protein, active, 10 µg

• 分類程式碼代碼: 12352202
• eCl@ss: 32160405

屬性

• 重組細胞: expressed in baculovirus infected Sf21 cells
• 品質等級: 100
• 描述: protein target NEK11
• 純化經由: (Ni²⁺/NTA-agarose)
• 技術: activity assay: suitable
• UniProt登錄號: Q8NG66
• 基因資訊: human ... NEK11(79858)

描述

一般說明

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

品質

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

物理性質

59.3kDa

儲存和穩定性

6 months at -70°C from date of shipment

分析報告

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H317
• 防範說明: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危險分類: Skin Sens. 1
• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable