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Merck
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重要文件

14-692-M

Sigma-Aldrich

DAPK1 Protein, active, 10 µg

Active, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

100
300

重組細胞

expressed in baculovirus infected Sf21 cells

分子量

Mw 60.9 kDa

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

基因資訊

human ... DAPK1(1612)

一般說明

N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296

生化/生理作用

Protein Target: DAPK1

品質

routinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)

儲存和穩定性

stable 6 months at -70°C from date of shipment

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Epigenetic change in pituitary tumorigenesis.
Farrell, W E and Clayton, R N
Endocrine-Related Cancer, 10, 323-330 (2003)
DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death.
Bialik, Shani and Kimchi, Adi
Seminars in cancer biology, 14, 283-294 (2004)
The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases.
Shohat, Galit, et al.
Biochimica et Biophysica Acta, 1600, 45-50 (2002)
Anastasia V Velentza et al.
Pharmacology & therapeutics, 93(2-3), 217-224 (2002-08-23)
Death-associated protein kinase (DAPK) is a calmodulin-regulated serine/threonine protein kinase associated with neuronal cell death in animal models of disease. The recent determination of the 1.5A crystal structure of the catalytic kinase domain of DAPK, the discovery of amino acid

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