14-440-M

PKA蛋白，重组，10 µg

Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.

• 分類程式碼代碼: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

屬性

• 生物源: human
• 品質等級: 100
• 重組細胞: expressed in E. coli; expressed in BL21 DE3 cells
• 產品線: Upstate^®
• 形狀: liquid
• 比活性: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.); 8580 U/mg
• 儲存期限: 1 yr
• 分子量: M_w 40.7 kDa
• 純化經由: chromatography
• 物種活性: human
• 製造商／商標名: Upstate^®
• 技術: activity assay: suitable (kinase)
• 溶解度: water: soluble
• 登錄號: (FUNCTION: SwissProt: P17612 # Phosphorylates a large number of substrates in the cytoplasm and the nucleus. ); NM_002730.3
• NCBI登錄號: NM_002730.3; NM_207518.1
• UniProt登錄號: P17612
• 儲存溫度: −70°C
• 基因資訊: human ... PRKACA(46909581)

描述

一般說明

Research area: Cell Signaling

Product Source: Expressed in E.coli BL21 (DE3) pLysS cells Recombinant human full length PKA, catalytic subunit type alpha, untagged Protein kinase A (PKA) is a serine protein kinase and heterotetrameric holoenzyme that targets serine and threonine residues.

Recombinant human full length PKA, catalytic subunit type alpha, untagged

生化／生理作用

Protein Target: PKA; Target Sub-Family: AGC. Protein kinases are vital for integrating signaling networks within eukaryotic cells. In Hedgehog-responsive cells, PKA is crucial for regulating proliferation and fate determination by influencing Hedgehog signaling transduction. PKA has numerous targets that are linked to adhesion or migration.

包裝

也提供250 µg的规格-订购250 µg的规格时，请致电咨询价格和供货情况，参考目录号14-440M。

Also available in 10 μg size and in bulk

品質

通过体外Kemptide底物的磷酸化进行常规评估

routinely evaluated by phosphorylation of Kemptide substrate in vitro

標靶描述

PKA

聯結

替代：14-114

外觀

磷酸纤维素P11色谱法

儲存和穩定性

在-70°C下保存1年

其他說明

比活相关数据，请参阅检验报告以获取该酶的单独批次。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1