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Merck
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重要文件

14-246-M

Sigma-Aldrich

p38γ/SAPK3 Protein, active, 10 µg

Active, recombinant GST fusion protein corresponding to full length human p38γ/SAPK3, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

重組細胞

expressed in E. coli

分子量

Mw 69 kDa

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

基因資訊

human ... PEBP1(5037)

一般說明

Product Source: expressed in E. coli
Recombinant GST fusion protein corresponding to full length human p38γ/SAPK3

生化/生理作用

Protein Target: p38γ/SAPK3
Target Sub-Family: CMGC

品質

Routinely evaluated by phosphorylation of MBP in vitro

儲存和穩定性

6 months at -70°C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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The hepatitis B virus HBx protein inhibits caspase 3 activity
Gottlob, K., et al
The Journal of Biological Chemistry, 273, 33347-33353 (1998)
A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)
S P Davies et al.
The Biochemical journal, 351(Pt 1), 95-105 (2000-09-22)
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine/threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many
Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif

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