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Key Documents

104662

SAFC

Cellvento® ModiFeed Sial+ COMP

greener alternative

Chemically defined cell culture feed - EMPROVE® CCM

製藥生產

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About This Item

分類程式碼代碼:
41106213

品質等級

描述

shipped with cooling packs

產品線

Cellvento®

形狀

dry powder

環保替代產品特色

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

技術

cell culture | mammalian: suitable

環保替代類別

儲存溫度

2-8°C

一般說明

Cellvento® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO or other production media.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

應用

Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes

特點和優勢

  • Reduced complexity in fed-batch process
  • Complete feed maximizing galactosylation
  • Highly concentrated to reduce required feed volume
  • Compacted format for conventient handling
  • Higher liquid feed stability at room temperature

數量

Formulated to contain 155.8 grams of powder per liter of feed.

法律資訊

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

分析證明 (COA)

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